Sirnaomics Inc. (Sirnaomics) and Precision NanoSystems Inc. (PNI) jointly announced a partnership on the development and manufacture of Sirnaomics polypeptide nanoparticle-based RNAi therapeutic product. This strategic joint effort includes the execution of a NanoAssemblr® platform license and supply agreement, plus successful production of multiple batches of Sirnaomics drug product candidates, STP705 and STP707, for ongoing IND enabling safety and toxicity studies, as well as several clinical studies.
Sirnaomics’ founder, president and CEO, Dr. Patrick Lu said, “As the leader in RNAi therapeutics specialized in polypeptide nanoparticle formulation, we are so excited to see the further advancement of our process development and large scale product manufacturing, using PNI’s NxGen™ microfluidic technology. In working with PNI’s team and the NanoAssemblr platform, we were able to establish a robust manufacturing process from a nominated drug candidate to GMP manufacturing in just a few months, greatly accelerating our drug development process”. Sirnaomics is currently using these batches produced with NxGen™ for non-human primate safety toxicity studies and clinical studies.”